SYPHILITIC LEUCODERMA AND THE PIGMENTARY SYPHILIDE

Leucoderma

[Disseminated nodulo-squamous syphilide].

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Leucoderma in early syphilis.

CASE 1 A 25-year-old man first noticed depigmented lesions on the face and neck; a few days later he developed asymptomatic erythematous papular and scaly lesions over the trunk and extremities, and moist papular lesions on the scrotal skin. Two weeks later when he reported to us, some of the trunk lesions had also become depigmented. Four months earlier after an extramarital sexual exposure, t...

Treatment for Leucoderma

Pigmentary Disorders

Many factors have been implicated for the etiology of melasma, but the exact cause of this hypermelanosis is poorly understood. However, it is considered to result from solar radiation and genetic predisposition. Moreover, pregnancy, oral contraception and hormone replacement therapy with natural and synthetic oestrogens, have been involved in the pathogenesis of this hypemelanosis. Despite the...